New oral anticoagulants for prevention of ischemic stroke in patients with nonvalvular atrial fibrillation: practical issues

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New oral anticoagulants (NOAC) have advantages over warfarin in efficacy and safety in patients with nonvalvular atrial fibrillation (AF). The article reviews certain practical issues of treatment with NOAC: 1) should we take into account the type of AF when assessing a need in anticoagulation; 2) can we use NOAC in patients with valvular disease; 3) anticoaulation in patients with AF and myocardial infarction; 4) follow-up of patients treated with NOAC.

Key words

Atrial fibrillation, ischemic stroke, anticoagulation, new oral anticoagulants.