Currently, there are 8 approved angiotensin receptor blockers (ARA) in the Russian Federation. They have different chemical structure and clinical efficacy. ARA are widely used for the treatment of arterial hypertension, heart failure and diabetic nephropathy, particularly in patients who do not tolerate ACE inhibitors. ARA are well-tolerated both in monotherapy and in combination with other medications. The review summarizes comparative pharmacokinetics and pharmacodynamics of different ARA.
Angiotensin receptor blockers, antihypertensive treatment, pharmacokinetics.