Pathogeneticreconstructionofdizziness inpatientswith brain circulatory disorder asabasis for effective treatment

Dizziness is one of the most common complaints in patients with a diagnosis of encephalopathy associated with circulatory disorder. Moreover, dizziness predicts spontaneous falls associated with a higher risk of fractures of upper and lower extremities. In these patients, dizziness develops as a result of the reduction in the number of neuronal synapses that mediate balance at rest and during walking. Periventricular leucoareosis that can be shown by MRI seems to be а morpho logical substrate for dizziness. Treatment for balance disorder should include modification of risk factors of stroke and induction of neuroplasticitybyregular training and administration of drugs that modulate different neurotrophic factors including brain-derived neurotrophic factor (BDNF).

Key words

Dizziness, brain-derived neurotrpohic factor(BDNF), vinpocetine.