Comparison of classification criteria for giant cell arteritis

Download in PDF


To compare the diagnostic value of classification criteria for giant cell arteritis (GCA).

Material and methods

In a retrospective study, we evaluted the 1990 American College of Rheumatology (ACR) criteria, 2016 revised ACR criteria and 2022 ACR and European Alliance of Associations for Rheumatology (EULAR) criteria for GCA. Their diagnostic value was determined using the binary classification quality assessment methods.


Eighty four GCA patients (63 females, median age 67 years) with or without polymyalgia rheumatica (PMR) comprised the study group, whereas 46 patients with PMR (39 females, median age 66 years) were enrolled in the control group. The 2016 revised ACR and 2022 ACR/EULAR criteria had higher sensitivity (71.4% and 71.4%, respectively) than the 1990 ACR criteria. Compared with other criteria, the 2022 ACR/EULAR criteria had better specificity (97.8%), predicted values of positive result (98.4%) and negative result (65.2%), likelihood ratio of positive test result (32.9) and negative result (0.3), Youden's J index (0.695), AUC (0.846) and Acc (80.8%). The 2022 ACR/EULAR criteria were informative for both cranial and constitutional phenotypes of GCA.


The 2022 ACR/EULAR classification criteria for GCA have a higher value in established large vessel vasculitis compared to the 1990 ACR and 2016 ACR criteria.

Key words

Giant cell arteritis, polymyalgia rheumatica, phenotypes, classification criteria.